Asclepigenia was the daughter of a philosopher called Plutarch, who headed the Neoplatonist school in Athens. He educated his daughter (and her brother, Hierius) in philosophy and mysticism. In time, (much like Hypatia in Alexandria) she too became a teacher.
Asclepigenia and her father followed a syncretic system which united traditional Platonic and Aristotelian philosophies with pagan ritual and magic.
When Plutarch died in 430, he passed the school onto his daughter. She taught metaphysics, cosmology and theology, all of which attempted to understand and predict the will of fate (or the gods) and influence the outcomes.
Asclepigenia is known to us largely because she taught the philosopher Proclus, and almost all of the information we have on her comes from The Life of Proclus by Marinus.
Ancient Women Philosophers: 600 B.C.-500 A. D. – M.E. Waithe